[Objective] This study aims to investigate the improvement effect of cellulose-based soil amendments prepared from corn cob and humic acid on the erosion resistance of sandy soil. [Methods] One or two mixtures of laccase and lignin peroxidase, three enzyme activity gradient levels, two corn cob addition masses, and a fixed amount of humic acid, were set to synthesize cellulose-based soil amendments through an aqueous solution polymerization method. Meantime, the characteristics of enzymatic hydrolysis products and functional groups of amendments were performed using infrared spectroscopy. The water retention capacity and network characteristics of the amendments were analyzed based on their swelling characteristics. In addition, the improvement effect of amendments on the erosion resistance of sandy soil was also evaluated based on the parameters related to mechanical and water stable aggregates. [Results] (1) The water absorbency of the cellulose-based soil amendments was about 0.61-4.84 times that of pure humic acid based amendments. In which, the soil amendment prepared by adding 4 g of enzymatic hydrolysis products of laccase (20 U) and lignin peroxidase (20 U) hydrolysate, had the highest water absorbency with a value of 66.7 g/g. The swelling process of the soil amendment corresponded to Schott's second-order kinetic model. (2) Compared to the control group (CK) , the addition of 1% amendments (Lac3-4, Lip3-4 and LLP3-4) synthesized by the three different enzymatic hydrolysis schemes increased the soil saturated water content by 20%-60%. LLP3-4 can increase the content of mechanical large aggregates and water stable large aggregates (>0.25 mm) by 6.15 and 14 times, increase the average weight diameter and geometric average diameter of soil by 45% and 46.67%, and reduce the fractal dimension by 21.36%, respectively. [Conclusion] Cellulose-based soil amendments prepared by dual enzyme pretreatment scheme can significantly enhance the water retention capacity and corrosion resistance of sandy soil.