[Objective] The spatial distribution of land use/cover types of different major function-oriented zoning (MFOZ) areas in the Fuzhou metropolitan area in 2030 was simulated, and the future development trend of the land spatial patterns was predicted. [Methods] Based on multi-source data such as DEM and land use/cover, road network, nighttime light images and meteorological data, the FLUS-Markov model was used to predict and compare the land use/cover structure of the metropolitan area in 2030 based on zoning simulation and overall simulation in order to explore differences in the spatial and temporal change intensity of land use/cover of MFOZ. [Results] ① In 2020, the kappa coefficients of the simulation results of MFOZ in the Fuzhou metropolitan area were all above 0.85, indicating that the combination of key parameters in the model could effectively simulate the spatial distribution pattern of land use/cover in different functional areas; ② Compared with the overall simulation, the better indication of single land use dynamic degree, comprehensive land use dynamic degree and land use degree in zoning results showed that, the zoning simulation was more suitable for future regional land use/cover planning. [Conclusion] The zoning simulation results of the Fuzhou metropolitan area in 2030 were more consistent with the development goals of MFOZ. Therefore, the future regional land use planning could be worked out combined with the development characteristics of MFOZ to propose the key directions of economic development and ecological protection in each region.