[Objective] The coupling coordination relationship and evolution trend of the agricultural eco-economic system in the loess hilly and gully regions was determined, in order to provide a basis for scientifically evaluating the ecological economic benefits of the region, and for realizing the coordination and sustainable development of agricultural eco-economics.[Methods] Based on agro-ecology and agro-economy data from Wuqi County, Shaanxi Province, an evaluation index system for the agro-ecology and agro-economy system was constructed. The comprehensive evaluation index, coupling coordination state, and coupling degree evolution trends for the agro-ecology and agro-economy systems were analyzed by using the entropy weight method, coupling coordination degree model, and coupling degree model.[Results] From 1990 to 2019, the comprehensive evaluation index of agricultural ecology at Wuqi County initially decreased and then increased. The comprehensive evaluation index of the agricultural economy followed the pattern of relatively rapid rise-stable development-rapid rise. The coupling coordination index increased from 0.29 to 0.63. This increase reflected the coordinated development of agricultural ecology and the agricultural economy in the region that has continuously strengthened over time, and the state of coupling coordination that has evolved from a slight imbalance to a primary level of coordination. The degree of coupling showed a downward trend followed by an upward trend, and the system has transitioned from a depletion development stage to coordinated development, indicating that the agricultural eco-economic system at Wuqi County was constantly developing in a coordinated manner.[Conclusion] We should continue to optimize the industrial structure based on ecological protection and adjust the relationship between ecological and economic development to better coordinate the development of the agricultural ecological environment and the agricultural economy in loess hilly and gully area.