[Objective] The changes of soil water and salt under different intercropping patterns of Lycium chinense in saline-alkali soil were researched in order to provide scientific basis for the improvement and utilization of saline-alkali land.[Methods] Four treatments of L. chinense intercropping with Medicago sativa, Brassica napus, Suaeda glauca and L. chinense monoculture were set up to analyze soil water and salt changes and soil salt balance under different intercropping modes.[Results] The soil moisture content of each treatment in the 0-60 cm soil layer showed that the intercropping M. sativa(13.67%) > intercropping B. napus (13.02%)> intercropping S. glauca(12.22%) > control(11.86%), and it was not obvious in the 60-100 cm soil layer. Compared with the control, the soil salinity of intercropping M. sativa, intercropping B. napus and intercropping S. glauca decreased by 6.91, 5.82 and 2.21 g/kg in the 0-40 cm soil layer, respectively. Soil desalination rates of intercropping M. sativa, intercropping B. napus and intercropping S. glauca and CK were 40.38%, 26.52%, 9.00% and -60.66% in 0-100 cm soil layer, respectively. Except for control, the soil of other treatments was all desalinated.[Conclusion] Different intercropping patterns of saline-alkali mantle can effectively increase soil water content, reduce soil salinity, and improve saline-alkali land.