[Objective] To establish optimization decision model of coal dust inhibitors in order to provide a useful theoretical reference for scientific evaluation and decision of coal dust inhibitor.[Methods] Based on the technique of order preference by similarity to ideal solution (TOPSIS), seven evaluation indexes were selected, and then weights were confirmed by using the pull-up method to avoid the subjectivity of decision maker.[Results] This model was applied to evaluate 10 research results of coal dust inhibitors in the last ten years. The results showed that the degradation dust suppressant was the best solution, followed by the coal dust inhibitor, while oxidized starch grafted acrylic acid acrylamide dust suppressant was the worst.[Conclusion] The model can effectively evaluate the comprehensive performance of dust suppression scheme by quantitative data, and which is of great importance for scientific decision making.