[Objective] The objective of this study is to evaluate the elution effect of α-amylase and tea saponin hybrid liquid on heavy metals such as Cd, Pd in soil, in order to provide a more accurate scientific basis for remediation of heavy metal contaminated soil.[Methods] Cd, Pd contaminated topsoil were selected as the study object, enzymes and tea saponin hybrid liquid was used to remediate the heavy metal contaminated soil. The changes of Cd, Pb before and after leaching were investigated.[Results] The removal efficiency of Cd and Pd were 88.87% and 43.97%, respectively. When the reaction time was 12 hours, pH value was 4.0, the reaction temperature was 30℃ and the ratio of tea saponin solution and enzymes solution was 4:1. The analysis of heavy metals before and after leaching showed that acid extractable and reducible metals were easier to remove. The content of Cd and Pd in soil after leaching reached up to the grade Ⅱ standard of soil environmental quality.[Conclusion] There is a synergistic enhancement effect between tea saponin and enzymes solution. The combination of enzymes and tea saponin has great effects on the removal of heavy metals from contaminated soil. The combinations of α-amylase and tea saponin have bright prospects in bioremediation of heavy metals in contaminated soil.