[Objective] To analyze the spatial and temporal variation characteristics of drought/flood disasters and to divide drought/flood grade of Guangdong Province from 1960 to 2012.[Methods] Wavelet analysis, Markov chain, Mann-Kendall mutation test, empirical orthogonal function and Kringing method were used.[Results] (1) As for temporal variation, the average annual rainfall of Guangdong Province is on the rise with 28 a, 13 a and 6 a time scale oscillation cycles; (2) Frequency of drought/flood disasters and the situation of drought/flood in the next few years have good responsive association with temperature changes. (3) As for spatial variations, the east and the west zones of Guangdong Province are likely undergoing flooding, while, Guangning-Guangzhou-Taishan region is easily being attacked by drought.[Conclusion] The drought/flood disasters increase after abrupt change of temperature, and there is a certain responsive relationship between drought/flood disasters and temperature changes.