[Objective] This paper aimed to understand the effects of sewage sludge organic fertilizer application on the amendment of lead-zinc mine tailings through the measurements of growth responses of four potted plants and heavy metal accumulation in them, in order to provide a theoretical basis for the repairing and improving of tailings by rational utilization of sludge organic fertilizer.[Methods] We adopted pot experiment and used four plants named Lolium multiflorum, Trifolium repens, Melilotus suaveolens and Astragalus adsurgens, as materials.[Results] It showed that the height, root length, biomass of plants reached the maximum when 20 g/kg fertilizer was applied. The chlorophyll a+b contents in the four plants with fertilization treatment were higher than that of the control without fertilization. The more sludge organic fertilizer was applied, the lower content of MDA in Lolium multiflorum,Trifolium repens were measured. The contents of Pb, Zn, Cd inLolium multiflorum, Trifolium repens, Melilotus suaveolens reached the maximum when fertilizer was 10 g/kg, and decreased when fertilizer was 20 g/kg.[Conclusion] It indicates that with the increased application of sludge organic fertilizer, the amount of heavy metals in plants will decrease. Sludge organic fertilizer can help to alleviate the poisoning effects of heavy metals on plants.